SNPs and TFBS Associated with High Altitude Sickness*

Buroker, Norman E. and Ning, Xuehan and Zhou, Zhaonian and Li, Kui and Cen, Weijun and Wu, Xiufeng and Zhu, Weizhong and Ronald Scott, C. and Chen, Shihan (2013) SNPs and TFBS Associated with High Altitude Sickness*. Open Journal of Blood Diseases, 03 (03). pp. 85-93. ISSN 2164-3180

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Official URL: https://doi.org/10.4236/ojbd.2013.33018

Abstract

The rSNPs for the genes AKT3 (rs4590656), EGLN1 (rs480902), eNOS3 (rs1007311), and VEGFA (rs699947, rs13207311, rs1570360, rs2010963) have been significantly associated with the physiological parameters in high altitude sickness Han or Tibetan Chinese patients at the Qinghai-Tibetan plateau. The alleles of each rSNP have been found to create unique transcriptional factor binding sites for transcription factors that affect the process of hypoxia gene expression in this high altitude hypoxia environment.

Item Type:	Article
Subjects:	Afro Asian Archive > Medical Science
Depositing User:	Unnamed user with email support@afroasianarchive.com
Date Deposited:	07 Apr 2023 09:00
Last Modified:	30 Jul 2024 13:59
URI:	http://info.stmdigitallibrary.com/id/eprint/409

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