Evaluation of Pain and Anxiety Levels Related to Diagnostic Punch Biopsy in Dermatology Outpatients: A Pilot Study

Aim: Literature data on the anxiety levels and pain perception during punch biopsy are lacking. Thus, the aim of the present study is to evalute the anxiety levels and pain perception during punch biopsy.

Study Design: This is a prospective, single-center pilot study conducted with the approval of the institutional review board.

Place and Duration of Study: Department of Dermatology, Afyon Kocatepe University, between May 2015 and June 2015.

Methodology: This study included 40 dermatology outpatients underwent a punch biopsy. Demographic data, biopsy site, and previous history of any interventional procedure were noted. Pre- and post-procedural anxiety levels were assessed using the State-Trait Anxiety Inventory-1, and perception about pre-procedural waiting period and pain perception during biopsy were assessed via 10-point visual analog scales. Furthermore, the association between anxiety and pain levels, and perceived waiting periods were investigated.

Results: In all, 60% of the patients were female (mean age: 43.3±16.3 years). The mean pre-procedural anxiety score was 41.3±10.1. The mean pain score was 3.45±2.8. Pain scores did not correlate with pre-procedural anxiety scores (P = 0.104). However, pre-procedural waiting period scores correlated positively with pre-procedural anxiety level (P = 0.028) and pain scores (P < 0.001).

Conclusions: The punch biopsy was associated with some pain and anxiety. And the perceived waiting period affected pain and anxiety level. Thus, shortening pre-procedural waiting periods may help in relieving pain and anxiety.